Individuality takes center stage at Grammys


Fun. helped break up the sound of dance and electronic music on Top 40 radio with its edgy pop-rock grooves. Frank Ocean made a bold statement in R&B — with an announcement about his sexuality and with his critically revered, multi-genre album, "channel ORANGE." And Mumford & Sons continued to bring its folk-rock swag and style to the Billboard charts with its sophomore album.


They all were rewarded Wednesday when The Recording Academy announced the nominees for the 2013 Grammy Awards.


Those acts, who scored the most nominations with six each, were joined by typical Grammy contenders like Jay-Z and Kanye West, who also got six nominations. The Black Keys' drummer, Dan Auerbach, is also up for six awards, thanks to his nomination for producer of the year. His band earned five nods, along with R&B singer Miguel and jazz pianist Chick Corea.


"It feels like alternative music is back," said fun. guitarist Jack Antonoff. His band's gold-selling "Some Nights" is up for album of the year, competing with Black Keys' "El Camino," Mumford & Sons' "Babel," Jack White's "Blunderbuss" and "channel ORANGE," the major label debut from Ocean.


Fun. is nominated in all of the major categories, including best new artist, and record and song of the year for its breakthrough anthem "We Are Young."


Ocean, whose mother attended the nominations special, scored nods in three of the top four categories. His song "Thinkin Bout You" — which he originally wrote for another singer — will compete for record of the year with Black Keys' "Lonely Boy" and four No. 1 hits: Taylor Swift's "We Are Never Ever Getting Back Together," ''Somebody I Used to Know" by Gotye and Kimbra, Kelly Clarkson's "Stronger (What Doesn't Kill You)" and "We Are Young" by fun.


Song of the year, too, features some No. 1 hits, including fun. and Clarkson's jams, as well as Carly Rae Jepsen's viral smash "Call Me Maybe." But then there's Ed Sheeran's "The A Team," a slow groove about a homeless prostitute, and Miguel's "Adorn," the R&B singer-songwriter's crossover hit.


"It's like one of those songs that wrote itself and I was the vessel," the 26-year-old said in an phone interview from New York City late Wednesday, where he performed with Trey Songz and Elle Varner.


While Miguel's excited to compete for song of the year, he's more thrilled about his sophomore album's nomination for best urban contemporary album, a new category that recognizes R&B albums with edge and multiple sounds.


"That's a huge complement to say that your entire body of work was the best of the year," he said of "Kaleidoscope Dream." ''That's the one that means the most to me. I'm really hoping maybe, just maybe."


Miguel, along with Gotye, Alabama Shakes and the Lumineers, is part of the pack of nominees who have showcased individuality and have marched to the beat of their own drum in today's music industry.


Though nominated albums by The Black Keys and Mumford & Sons are platinum-sellers, their songs are not regularly heard on Top 40 radio. Electronic and dance music, which has dominated radio airplay for a few years, were left out of the top awards this year. Also, One Direction — the boy band that released two top-selling albums this years and sold-out many arenas — was snubbed for best new artist.


Lionel Richie has one of the year's top-selling albums with his country collaboration collection, "Tuskegee," but he didn't earn any nominations. And Nicki Minaj, who released a gold-selling album this year and had a hit with "Starships," wasn't nominated for a single award.


Jay-Z and West dominated the rap categories, a familiar refrain at the Grammys. Nas scored four nominations, including best rap album for "Life Is Good." Jeff Bhasker, the producer behind fun.'s breakthrough album, also scored four nods.


Swift, who released her latest album, "Red," after the Grammy eligibility date, still scored three nominations, including two for "Safe & Sound" with The Civil Wars. Country acts were mainly left out of the major categories this year, though the genre usually has success at the Grammys. Aside from Swift's pop song competing for record of the year, there is 21-year-old Hunter Hayes, who is up for best new artist against fun., Ocean, Alabama Shakes and the Lumineers.


"I'm so proud to be, as you say, representing country music in the new artist category," said Hayes, who is also nominated for best country album and country solo performance. "I don't even feel worthy of saying that, but it's so cool for me to be able to say that."


Swift hosted the CBS special with LL Cool J and it featured performances by The Who and Maroon 5, who received multiple nominations.


The five-year-old nominations show spent its first year outside Los Angeles, making its debut in Nashville, Tenn., at the Bridgestone Arena. It marked the largest venue the show has been held in.


The 55th annual Grammy Awards take place Feb. 10 in Los Angeles.


___


Online:


http://www.grammys.com


___


AP Music Writer Chris Talbott and AP Writer Caitlin R. King in Nashville contributed to this report.


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Well: Holding on for the Wedding

As my patient looked on, his wife took the framed photograph out of a nondescript manila mailer, the type with bubble wrap on the inside, and handed it to me gingerly. It was clear they both considered it to be precious cargo.

“You can see I made it to the wedding,” he said, smiling broadly, as I studied the image of him in a suit, locking arms with his granddaughter, the bride. The two of them were bordered by the opened doors of the church, stained glass windows on either side, his face bearing that familiar look of consuming love, joy and pride — along with a little fear, that at any moment he might start sobbing in front of all of his buddies and co-workers attending the ceremony. I have the same photograph in my own wedding album, of my father-in-law with my wife-to-be.

“You should have heard the gasp from everyone in the church when he came through those doors with our granddaughter,” his wife exclaimed. “I mean, no one thought he would even be there!”

“My granddaughter and I had been planning it for months, but we didn’t tell anyone,” my patient went on, explaining that he and his wife had raised the girl for several years while their daughter, who had gotten pregnant in her teens, could get back on her feet.

When it came to his health, my patient is the type of guy about whom you might say if he didn’t have bad luck, he wouldn’t have any luck at all. Years earlier, he was treated for colon cancer. Now, possibly as a result of that treatment, he had leukemia. But he also had a completely different type of bone cancer, and the kicker — advanced lung cancer.

He wasn’t the first patient I had ever treated with multiple cancers, and in general we approach people like him by going in order of treating the most serious cancers first, and working our way down to the less serious ones. In one respect, he was lucky: he looked a heck of a lot better than his medical chart. As leukemia and lung cancer often represent the worst of the worst, we tried treating both at the same time. The leukemia went into remission. The lung cancer didn’t.

Within oncology, it is taken as almost a truism that people die only after they have said their goodbyes to their immediate family, or achieved some life milestone. Countless times I have seen comatose patients linger until a child flies in from California, only to pass hours after that child’s arrival.

A study that appeared in The Journal of the American Medical Association in 2004 looked at whether people die soon after a milestone. In it, the authors analyzed death certificates from more than 300,000 people dying with cancer in Ohio from 1989 to 2000, and whether those people were more likely to die immediately after a birthday, Christmas or Thanksgiving. It turns out that these people were no more likely to die after these events than before, and the authors concluded that cancer patients are not able to postpone their deaths to survive such significant occasions.

The study was misguided, though: the authors asked the wrong question. The last time I looked forward to a birthday was half a lifetime ago when, for the first time, I could walk proudly into a bar without having to proffer my grungy fake I.D. And while I enjoy holidays, what motivates me to brave the traffic on I-80 with a car full of children and a DVD player on the fritz is not my enduring respect for pilgrims; it is the chance to be with the family I see far too infrequently.

“The weekend before the wedding was a close call,” my patient said. “I couldn’t move my leg or my arm, and that CT scan showed the lung cancer in my brain….” he trailed off.

“But that pill you prescribed really did the trick,” his wife picked up. “He could walk again after a few days.”

“Even if it hadn’t, if I’d had to tape my arm to my body and walk with a splint, I wouldn’t have missed it,” my patient said with a fierce look in his eyes.

I wanted to hang on to the photo, it represented such determination, but reluctantly handed it back. I said my goodbyes to them in clinic, then headed to the workroom, where one of the leukemia nurses approached me.

“When do you want to see him again — in four weeks or in five?” the nurse asked. I had the hardest time answering, and she gave me a knowing smile, understanding why I was hesitating.

“I don’t think it makes a difference, now that his granddaughter is married,” I answered.

He did come to clinic, just one more time. He was wearing a sweatshirt with the wedding photo silkscreened on the front, and underneath the caption, “Mission Accomplished.”

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Jobless claims fall sharply for the week













Jobless numbers


Jobless claims were sharply down last week, back to just about the weekly average for the 10 weeks before Hurricane Sandy arrived.
(Bloomberg)































































WASHINGTON -- New jobless claims last week fell much more sharply than expected, a reassuring sign that the damaging effects from Hurricane Sandy to the labor market have largely passed. 


The Labor Department said Thursday that 370,000 people filed initial claims for unemployment insurance in the week ended Saturday, down from a revised 395,000 in the prior week. The latest claims number was just about the weekly average for the 10 weeks prior to the storms.


The Labor Department on Friday will issue its jobs report for November, and that is expected to reflect the disruption to commerce and temporary loss of work after the so-called superstorm knocked out power and caused severe damage in the Northeast, particularly New York and New Jersey.





The economy added 171,000 new jobs in October, according to the Labor Department, but analysts are forecasting a number closer to 100,000 for November because of Hurricane Sandy. A report earlier this week by payroll processor Automatic Data Processing Inc. estimated that Hurricane Sandy shaved 86,000 private-sector jobs in November, likely resulting in growth of 118,000 payrolls at private employers for the month.


New jobless claims, which are an indicator of layoffs and labor market trends, had spiked to 451,000 in the first full week of November in the wake of the storms. The latest tally marked the third straight weekly decline and a near-complete reversal of the 90,000 jump in the week after the storms.






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Secure Communities is optional, Harris says









SAN FRANCISCO — California Atty. Gen. Kamala Harris told local law enforcement agencies Tuesday that they were not obligated to comply with a federal program whose stated goal is to deport illegal immigrants convicted of serious crimes.


It was Harris' first public assessment of Secure Communities. Under the program launched in 2008, all arrestees' fingerprints are sent to immigration officials, who may ask police and sheriff's departments to hold suspects for up to 48 hours after their scheduled release so they can be transferred to federal custody.


Although the intent may have been to improve public safety, Harris said that a review of data from March through June showed that 28% of those targeted for deportation in California as a result were not criminals. Those numbers, she noted, had changed little since U.S. Immigration and Customs Enforcement a year earlier pledged to reform the program to focus on the most serious offenders.





"Secure Communities has not held up to what it aspired to be," Harris said. The law enforcement bulletin she issued Tuesday stated that "immigration detainer requests are not mandatory, and each agency may make its own decision" about whether to honor them.


Harris said her office conducted its analysis after dozens of agencies across the state inquired about whether they were compelled to honor the ICE requests.


Some elected officials and local law enforcement have complained that — in addition to pulling in those found guilty of minor offenses or never convicted — Secure Communities had made illegal immigrants fearful of cooperating with police, even when they were the victims.


Harris, a former prosecutor, echoed that view Tuesday.


"I want that rape victim to be absolutely secure that if she waves down an officer in a car that she will be protected … and not fear that she's waving down an immigration officer," Harris said


While immigrant-rights advocates applauded her announcement, they said it did not go far enough. Allowing police chiefs and sheriffs to craft their own policies without state guidance, they said, could lead to disparate enforcement and enable racial profiling.


This "should eliminate the confusion among some sheriffs about the legal force of detainers," said Reshma Shamasunder, executive director of the California Immigrant Policy Center. "The only logical next step is a strong, statewide standard that limits these burdensome requests."


One attempt by legislators to do just that unraveled in October with Gov. Jerry Brown's veto of the Trust Act. The proposed law by Assemblyman Tom Ammiano (D-San Francisco) would have forbidden police departments to honor federal detainer requests except in cases in which defendants had been convicted of a serious or violent crime.


Ammiano on Monday reintroduced a modified version of the measure. Harris said she had opposed the bill's last iteration for going "too far" and had not seen the current version, but looked forward "to working with the governor and any of our lawmakers to take a look at what we can do to improve consistency."


"It's very difficult to create formulas for law enforcement," she said, noting that local agencies should have the freedom to determine which federal hold requests to honor. For example, she said, an inmate with five previous arrests for forcible rape but no convictions might still be deemed too great a risk for release.


Some law enforcement agencies, including the San Francisco Sheriff's Department and the Santa Clara County Sheriff's Department, have declined to comply with federal requests to hold non-serious offenders. Los Angeles Police Chief Charlie Beck followed suit last month, announcing that suspected illegal immigrants arrested in low-level crimes would no longer be turned over for possible deportation.


Los Angeles County Sheriff Lee Baca, who opposed the Trust Act, is among those who have argued that compliance with Secure Communities was mandatory.


On Tuesday, Los Angeles County sheriff's spokesman Steve Whitmore said that Harris' opinion was welcome guidance that may offer sheriffs more flexibility in how they deal with immigration detainees.


"The attorney general's opinion is going to be taken very seriously," Whitmore said. "The sheriff applauds it and is grateful for it." Baca, he added, has been working with the attorney general and the governor on the issue.


In a written response to Harris' announcement, a spokeswoman for Immigration and Customs Enforcement said the agency's top priorities were the deportation of criminals, recent border-crossers and repeat violators of immigration law.


"The federal government alone sets these priorities and places detainers on individuals arrested on criminal charges to ensure that dangerous criminal aliens and other priority individuals are not released from prisons and jails into our communities," the statement said.


lee.romney@latimes.com


cindy.chang@latimes.com


Romney reported from San Francisco and Chang from Los Angeles.





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Habla el hombre que definió qué significa ser un hacker












“Soy un hacker.” La frase la pronuncia, sin titubeos, Pekka Himanen, un finlandés de 39 años que publicó, en 2001, La ética del hacker y el espíritu de la era de la información , un libro fundacional en su análisis de lo que significa la tecnología moderna en nuestra sociedad, y la influencia que tendrán los hackers en la sociedad futura.


La entrevista está por comenzar. El punto de encuentro es un hotel céntrico de la ciudad de Buenos Aires, pero en lugar de recibirnos en el salón exclusivo reservado con este fin, el filósofo Himanen (recibido en la universidad de Helsinki a los 20 años) prefiere reunirse en el café del hotel, rodeado de gente y atento a su entorno.












Este hombre, que hoy es profesor en la Universidad de Arte y Diseño de Helsinki, y profesor visitante de la Universidad de Oxford y el Instituto IN3 de Barcelona, y miembro del Instituto Helsinki para la Tecnología de la Información (HIIT) es autor, también, de El Estado del bienestar y la sociedad de la información: el modelo finlandés , que realizó junto con el sociólogo español Manuel Castells.


Himanen llegó a nuestro país invitado por la Universidad Nacional de San Martín, la Universidad Diego Portales y por la Fundación OSDE, pero además de esta convocatoria también lo trajo una de sus grandes pasiones: la investigación. “Estamos estudiando, junto con Manuel Castells, qué tipo de modelo de desarrollo nuevo se necesita después de la crisis mundial. Me refiero a un modelo de desarrollo económico combinado con desarrollo humano. Creo que es fundamental combinar una economía sustentable con el bienestar sustentable”, sostiene al comenzar la entrevista. Según cuenta el filósofo, Argentina es parte de un gran estudio que está llevando a cabo en distintos países de América latina, Asia, África, Estados Unidos y Europa.


¿Usted se considera un hacker?


Sí, claro que sí. Para mí un hacker es alguien creativamente apasionado por lo que hace y quiere hacerlo con otros. No necesariamente tiene que tener que ver con las computadoras, se puede ser hacker del conocimiento o de cualquier otro campo. Es importante decir que utilizo el término hacker en el sentido original del término, que no quiere decir delincuente informático.


¿Y usted es hacker en qué área o con qué especialización?


Yo diría en la filosofía, investigación y quizás en la vida.


¿Cómo es eso?


La etica del hacker es un libro que también habla sobre la filosofía de vida, es decir, uno tiene que preguntarse a sí mismo: ¿cuál es mi pasión creativa? ¿Qué es lo que le da significado a mi vida? Esas son grandes preguntas que todos deberíamos considerar.


Popularmente el término hacker tiene una mala connotación pero según usted explica, es un error. En su libro menciona otro término: cracker ¿Cuál es la diferencia entre ambos?


Hacker quiere decir que la persona es creativamente apasionada por lo que hace, y lo quiere realizar con lo que yo denomino “interacción enriquecedora”, es decir con otras personas. Cracker, en cambio, es el delincuente informático, la persona que ingresa en los sistemas informáticos y esparce virus, entre otros delitos.


¿Por qué, entonces, los hackers son considerados delincuentes?


Todo comenzó en los medios de comunicación, en los inicios del software. Por aquel entonces los medios tomaron la palabra hacker y comenzaron a utilizarla como sinónimo de delincuente informático para hacerlo más atractivo y dar impacto en sus noticias, pero la palabra hacker no tiene nada que ver con la delincuencia informática.


Según su libro los hackers informáticos ponen a disposición gratuita de los demás su creación para que la utilicen, pongan a prueba y la desarrollen. ¿Cómo un hacker se transforma en Bill Gates? En otras palabras, ¿cómo se transforma un hacker en un hombre de negocios?


La ética hacker es una ética de trabajo creativa en la era informática que reemplaza lo que Max Weber describió como “ética de trabajo industrial” pero después depende de cuán abierto es uno en el desarrollo de otras cosas. No necesita ser cerrado para ser un éxito, por ejemplo Linus Torvalds está a favor de la apertura total y también ha tenido mucho éxito. Internet corre en Linux, tres de cada cuatro smartphones en el mundo corren en Linux, porque Android está basado en Linux. Pero más allá de eso no hay contradicciones, porque uno puede tener pasión creativa como empresario. Lo importante es dar suficiente nivel de apertura.


¿Cómo ayudan a la sociedad los hackers y las redes sociales en situaciones de conflicto, injusticia social o cuando no hay libertad de expresión?


En situaciones como la guerra de Kosovo o en la Primavera Árabe -levantamientos populares de países árabes realizados entre 2010 y 2012- la difusión de lo que estaba pasando fue a través de las redes sociales. Y es muy importante tener en cuenta que las redes sociales tienen un impacto en la vida real. Si pensamos en la Primavera Árabe, por ejemplo, algunos de los peores dictadores que nosotros pensamos que nunca dejarían el poder, colapsaron. Y las redes sociales colaboraron mucho en la caída de estos dictadores porque la Primavera Árabe estuvo organizada a través de Internet. También en Europa se produjeron hechos similares. Las redes sociales tuvieron gran protagonismo en el movimiento de “Los Indignados”, que produjeron cambios políticos en España y en Grecia.


¿Le parece que lo que escribió hace más de una década sigue vigente?


Sí. El libro es más actual ahora. Si uno toma, por ejemplo, el capítulo de open source o de código abierto, su utilización ha crecido exponencialmente si tenemos en cuenta que Internet corre en software en código abierto y se diseminan en varios equipos como teléfono, grabadores digitales y televisores. Probablemente uno no se de cuenta que está utilizando código abierto, pero todos lo estamos utilizando. En cuanto al trabajo empresarial, la nueva ética de pasión creativa enriquecedora está impulsando al Silicon Valley.


¿Cómo ve a la sociedad futura?


Creo que la gran pregunta es lo que hoy estamos investigando en el proyecto que estoy realizando, donde nos damos cuenta que el viejo modelo de desarrollo ha llegado a su fin y ahora tenemos que replantear las prácticas grandes en la economía, la sustentabilidad ecológica. Creo que vamos a necesitar del potencial completo de la cultura de la creatividad y hemos de desarrollar esa nueva forma de bienestar sustentable, especialmente la sustentabilidad ecológica. Debemos tener en cuenta que el planeta no tiene problema en cuanto al cambio climático, puede continuar sin nosotros, pero nosotros no podemos continuar sin el planeta.


Por último, ¿qué trata de decirnos con su libro?


Para mí la clave es que todos debemos preguntarnos: ¿cuál es mi pasión creativa, cuál es mi propósito significativo en esta vida?


Linux/Open Source News Headlines – Yahoo! News


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Capitalism and socialism wed as words of the year


NEW YORK (AP) — Thanks to the election, socialism and capitalism are forever wed as Merriam-Webster's most looked-up words of 2012.


Traffic for the unlikely pair on the company's website about doubled this year from the year before as the health care debate heated up and discussion intensified over "American capitalism" versus "European socialism," said the editor at large, Peter Sokolowski.


The choice revealed Wednesday was "kind of a no-brainer," he said. The side-by-side interest among political candidates and around kitchen tables prompted the dictionary folk to settle on two words of the year rather than one for the first time since the accolade began in 2003.


"They're words that sort of encapsulate the zeitgeist. They're words that are in the national conversation," said Sokolowski from company headquarters in Springfield, Mass. "The thing about an election year is it generates a huge amount of very specific interest."


Democracy, globalization, marriage and bigot — all touched by politics — made the Top 10, in no particular order. The latter two were driven in part by the fight for same-sex marriage acceptance.


Last year's word of the year was austerity. Before that, it was pragmatic. Other words in the leading dictionary maker's Top 10 for 2012 were also politically motivated.


Harken back to Oct. 11, when Vice President Joe Biden tangled with Mitt Romney running mate Paul Ryan in a televised debate focused on foreign policy — terror attacks, defense spending and war, to be specific.


"With all due respect, that's a bunch of MALARKEY," declared Biden during a particularly tough row with Ryan. The mention sent look-ups of malarkey soaring on Merriam-webster.com, Sokolowski said, adding: "Clearly a one-week wonder, but what a week!"


Actually, it was more like what a day. Look-ups of malarkey represented the largest spike of a single word on the website by percentage, at 3,000 percent, in a single 24-hour period this year. The company won't release the number of page views per word but said the site gets about 1.2 billion overall each year.


Malarkey, with the alternative spelling of "y'' at the end, is of unknown origin, but Merriam-Webster surmises it's more Irish-American than Irish, tracing it to newspaper references as far back as 1929.


Beyond "nonsense," malarkey can mean "insincere or pretentious talk or writing designed to impress one and usually to distract attention from ulterior motives or actual conditions," noted Sokolowski.


"That's exactly what Joe Biden was saying. Very precise," especially in conversation with another Irish-American, Sokolowski said. "He chose a word that resonated with the public, I think in part because it really resonated with him. It made perfect sense for this man to use this word in this moment."


An interesting election-related phenom, to be sure, but malarkey is no dead Big Bird or "binders full of women" — two Romneyisms from the defeated candidate's televised matchups with Obama that evoked another of Merriam-Webster's Top 10 — meme.


While malarkey's history is shaded, meme's roots are easily traced to evolutionary biologist Richard Dawkins, a Brit who coined the term for a unit of cultural inheritance, not unlike genes and DNA. The retired professor at the University of Oxford made up the word in 1976 for "The Selfish Gene," a book he published light years before the Internet and social media's capacity to take memes viral.


Sokolowski said traffic for meme more than doubled this year over 2011, with dramatic spikes pegged to political-related subjects that included Romney's Big Bird and binders remarks, social media shares of images pegged to Hillary Rodham Clinton texting and Obama's "horses and bayonets" debate rebuke of Romney in an exchange over the size of the Navy.


Dawkins, reached at home in Oxford, was tickled by the dictionary shoutout.


"I'm very pleased that it's one of the 10 words that got picked out," he said. "I'm delighted. I hope it may bring more people to understand something about evolution."


The book in which he used meme for the first time is mostly about the gene as the primary unit of natural selection, or the Darwinian idea that only the strongest survive. In the last chapter, he said, he wanted to describe some sort of cultural replicator.


And he wanted a word that sounded like "gene," so he took a twist on the Greek mimeme, which is the origin of "mime" and "mimesis," a scientific term meaning imitation.


"It's a very clever coinage," lauded the lexicographer Sokolowski.


Other words in Merriam-Webster's Top 10 for 2012:


— Touche, thanks in part to "Survivor" contestant Kat Edorsson misusing the word to mean "tough luck" rather than point well made, before she was voted off the island in May. Look-ups at Merriam-webster.com were up sevenfold this year over 2011.


— Schadenfreude, made up of the German words for "damage" and "joy," meaning taking pleasure in the misery of others, was used broadly in the media after the election. Look-ups increased 75 percent. The word in English dates to 1895.


— Professionalism, up 12 percent this year over last. Sokolowski suspects the bump might have been due to the bad economy and more job seekers, or a knowing "glimpse into what qualities people value."


___


Online: http://www.merriam-webster.com/


___


Follow Leanne Italie on Twitter at http://twitter.com/litalie


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Extended Use of Breast Cancer Drug Suggested


The widely prescribed drug tamoxifen already plays a major role in reducing the risk of death from breast cancer. But a new study suggests that women should be taking the drug for twice as long as is now customary, a finding that could upend the standard that has been in place for about 15 years.


In the study, patients who continued taking tamoxifen for 10 years were less likely to have the cancer come back or to die from the disease than women who took the drug for only five years, the current standard of care.


“Certainly, the advice to stop in five years should not stand,” said Prof. Richard Peto, a medical statistician at Oxford University and senior author of the study, which was published in The Lancet on Wednesday and presented at the San Antonio Breast Cancer Symposium.


Breast cancer specialists not involved in the study said the results could have the biggest impact on premenopausal women, who account for a fifth to a quarter of new breast cancer cases. Postmenopausal women tend to take different drugs, but some experts said the results suggest that those drugs as well might be taken for a longer duration.


“We’ve been waiting for this result,” said Dr. Robert W. Carlson, a professor of medicine at Stanford University. “I think it is especially practice-changing in premenopausal women because the results do favor a 10-year regimen.”


Dr. Eric P. Winer, chief of women’s cancers at the Dana-Farber Cancer Institute in Boston, said that even women who completed their five years of tamoxifen months or years ago might consider starting on the drug again.


Tamoxifen blocks the effect of the hormone estrogen, which fuels tumor growth in estrogen receptor-positive cancers that account for about 65 percent of cases in premenopausal women. Some small studies in the 1990s suggested that there was no benefit to using tamoxifen longer than five years, so that has been the standard.


About 227,000 cases of breast cancer are diagnosed each year in the United States, and an estimated 30,000 of them would be in premenopausal women with ER-positive cancer and prime candidates for tamoxifen. But postmenopausal women also take tamoxifen if they cannot tolerate the alternative drugs, known as aromatase inhibitors.


The new study, known as Atlas, included nearly 7,000 women with ER-positive disease who had completed five years of tamoxifen. They came from about three dozen countries. Half were chosen at random to take the drug another five years, while the others were told to stop.


In the group assigned to take tamoxifen for 10 years, 21.4 percent had a recurrence of breast cancer in the ensuing nine years, meaning the period 5 to 14 years after their diagnoses. The recurrence rate for those who took only five years of tamoxifen was 25.1 percent.


About 12.2 percent of those in the 10-year treatment group died from breast cancer, compared with 15 percent for those in the control group.


There was virtually no difference in death and recurrence between the two groups during the five years of extra tamoxifen. The difference came in later years, suggesting that tamoxifen has a carry-over effect that lasts long after women stop taking it.


Whether these differences are big enough to cause women to take the drug for twice as long remains to be seen.


“The treatment effect is real, but it’s modest,” said Dr. Paul E. Goss, director of breast cancer research at the Massachusetts General Hospital.


Tamoxifen has side effects, including endometrial cancer, blood clots and hot flashes, which cause many women to stop taking the drug. In the Atlas trial, it appears that roughly 40 percent of the patients assigned to take tamoxifen for the additional five years stopped prematurely.


Some 3.1 percent of those taking the extra five years of tamoxifen got endometrial cancer versus 1.6 percent in the control group. However, only 0.6 percent of those in the longer treatment group died from endometrial cancer or pulmonary blood clots.


“Over all, the benefits of extended tamoxifen seemed to outweigh the risks substantially,” Trevor J. Powles of the Cancer Center London, said in a commentary published by The Lancet.


Dr. Judy E. Garber, director of the Center for Cancer Genetics and Prevention at Dana-Farber, said many women have a love-hate relationship with hormone therapies.


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Netflix buys exclusive rights to Disney movies









Netflix Inc. has acquired exclusive U.S. rights to movies from Walt Disney Studios in a deal that catapults the Internet video-on-demand service into direct competition with pay TV giants such as HBO and Showtime.


The three-year agreement takes effect in 2016 and is a blow to the pay channel Starz, which currently has the rights to broadcast Disney movies, including its Pixar animated films and Marvel superhero pictures, about eight months after they are released in theaters.


Starz's sole remaining movie provider is now Sony Pictures. That partnership ends in 2016.





VIDEO: Disney buys Lucasfilm - Mickey meet Darth Maul


Disney has also agreed to give Netflix nonexclusive streaming rights to more of its older titles — including "Dumbo," "Pocahontas" and "Alice in Wonderland" — starting immediately.


Netflix's chief content officer, Ted Sarandos, called the deal "a bold leap forward for Internet television."


"We are incredibly pleased and proud this iconic family brand is teaming with Netflix to make it happen," he said.


Netflix stock soared on the news, rising $10.65, or 14%, to $85.65.


Shares in Starz's parent company, Liberty Media Corp., fell $5.49, or 5%, to $105.56.


Currently, Netflix has nonexclusive rights to movies from Paramount Pictures, Lionsgate and Metro-Goldwyn-Mayer via a deal with pay channel Epix, as well as an array of library titles from other studios. Its only exclusive movie rights come from independent studios such as Relativity Media and DreamWorks Animation. It also has a wide variety of television reruns.


Sarandos and Netflix Chief Executive Reed Hastings have long said the company wanted to get exclusive pay TV rights to films from one of Hollywood's six major studios to boost its online entertainment service.


PHOTOS: Disney without Pixar


However, Hastings has also at times downplayed the importance of new movies. Netflix previously had streaming rights to Disney and Sony movies via a deal with Starz. In January, investors expressed their concerns that the pending disappearance of those movies would hurt the service. Hastings said in a letter to investors that Disney films accounted for only 2% of domestic streaming and the loss would not be felt.


Since then, though, the Disney movie slate has become more attractive. At that time, Netflix did not have access to movies from Disney's Marvel superhero unit or the "Star Wars" titles from its pending acquisition of Lucasfilm Ltd.


The end of the Starz agreement accelerated a trend that has seen Netflix evolve into a television company, with reruns of shows such as "Mad Men" accounting for about two-thirds of the content streamed by users.


With several original programs launching next year, including the Kevin Spacey political drama "House of Cards," and a direct connection to a growing number of Internet-enabled televisions, Netflix is on the verge of standing on par with many TV networks.


Netflix charges $8 a month for its streaming service, while premium cable networks such as HBO cost $13 to $18 a month, and that's on top of a monthly bill for other channels that typically exceeds $50. It remains to be seen whether the addition of Disney products and more original programming could lead Netflix to increase its price.


PHOTOS: Hollywood back lot moments


The Netflix spending spree could continue, with Sarandos telling Bloomberg News on Monday that his company would bid for rights to Sony movies when its Starz deal expires.


Netflix might have a tougher time wresting away the rights to Warner Bros., 20th Century Fox or Universal Pictures releases from their current deals with HBO, which like Warner is part of Time Warner Inc. Paramount, Lionsgate and MGM are almost certain to stick with Epix, of which the trio are co-owners.





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Mexico port picks up slack from strike at L.A., Long Beach complex









ENSENADA — This sluggish port city is coming alive.


Standing atop a pier with a hulking cargo ship behind him, dock manager Rogelio Valenzuela Gonzalez motioned Monday toward four cranes as they plucked metal containers from the vessel.


Operators swiveled the cranes toward a line of flatbed trucks. Supervisors in reflective vests and hard hats watched from below, using two-way radios to dispatch trucks as they filled up.





Not even during the peak fall shipping season is this port so busy.


But a strike that has effectively shut down rival ports in Los Angeles and Long Beach has diverted ships south of the border. It has become a windfall for the port located about 50 miles from the border, its workers and the region's struggling economy.


"It's good for the workers' families," said Gonzalez, adding that the extra work will pay for additional Christmas presents. "We all know it's temporary, but it definitely helps out at the end of the year."


The Southern California strike ended its first week Monday, with negotiations continuing but no signs of an immediate resolution.


The strike by the International Longshore and Warehouse Union Local 63 Office Clerical Unit, which handles paperwork for incoming and outgoing ships, has crippled the nation's two busiest cargo ports.


The dispute centers on the charge by the union that employers — large shipping lines and terminal operators — have steadily outsourced jobs through attrition. The union says the employers have transferred work from higher-paid union members to lower-paid employees in other states and countries.


The employers dispute that claim, saying they've offered the workers full job security and generous wage and pension increases. Though the union has only 800 members, the 10,000-member dockworkers union is honoring the picket lines.


Economists estimate the effect of the work stoppage at $1 billion a day in forfeited worker pay, missing revenue for truckers and other businesses and the value of the cargo that hasn't been able to reach its destination. The two ports are directly responsible for an estimated 595,000 jobs in Southern California.


But while thousands of Southern California workers sit idle in Los Angeles and Long Beach, the walkout is giving Ensenada a hoped-for chance to showcase itself.


Collectively, Los Angeles and Long Beach handle 100 times more cargo each year than Ensenada.


Long seen as a backup port, Ensenada is eager to win more business from shippers inconvenienced by the second major work dispute at the L.A. and Long Beach ports in a decade.


"It's a great opportunity to show that the Port of Ensenada presents an alternative method for bringing in products from Asia and the Pacific Rim," said Kenn Morris, president of Crossborder Group, a San Diego consulting firm. "The Ensenada port can really show itself off as being something a lot of people hadn't expected."


Uncertain how long the strike may last, retailers have scrambled to find alternate ways to get their products onto shelves. Given their typically thin profit margins, retailers are concerned about the added shipping costs.


"These blockages are dead-weight losses to the system," said Carl Voigt, an international business professor at USC. "They raise costs for everybody. Everybody's goods and services are more expensive."


Ensenada is used to seeing the occasional cruise ship and maybe half a dozen cargo ships a week. Two ships have made unplanned dockings and unloaded cargo here in the last week. Three others have docked in Manzanillo, a Mexican port city 1,200 miles to the south of Ensenada.


Altogether, 17 ships bound for the L.A. or Long Beach port have been diverted elsewhere, including nine to Oakland, one to Mazatlan, Mexico, and one to Panama.


In Ensenada, dockworkers made quick work unloading 100 cargo containers from the Maersk Merlion. The giant cargo vessel was diverted over the weekend and docked early Monday morning.


Since late last week, Ensenada has been preparing for a hoped-for influx of diverted ships. The port has 200 dockworkers when operating at capacity, and an additional hundred clerical and customs workers.


Equipment is on standby. Workers are at the ready. And trucking lines have been placed on alert that cargo may need to be hauled.


"It's hard to guess how many ships we'll receive, but we are preparing for more," said Juan Carlos Ochoa, the port's trade development manager.


Ensenada is still handicapped by longer-standing obstacles, primarily its lack of railway access to move goods.


And for now, the cargo unloaded from the Maersk Merlion will sit at the port as the shipping line weighs whether to move it by truck to its final destination or have another ship pick up the containers at a later date.


The strike "is an extraordinary situation," Gonzalez said. "But it'll show our clients that this port is a good option. It's efficient, reliable and secure."


ricardo.lopez2@latimes.com


walter.hamilton@latimes.com


Lopez reported from Ensenada, and Hamilton from Los Angeles.





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US reacts with joy to royal baby news


WESTPORT, Connecticut (AP) — An heir to the British throne is on the way — and Americans may be as enthralled as the Brits.


This former colony has been riveted by the royal news that the former Kate Middleton is pregnant — perhaps as much as Britain, where such regal developments are taken in stride.


"We don't really have a princess here," said Kathy Gitlin, an elementary school teacher in Connecticut who was thrilled to hear that Kate is with child. "I'm an Anglophile, I love England, and I think it's wonderful that two people in love wanted to get married and start a family. It's great."


There are several reasons for the American public's pleasure in Kate's news, manifested not only by the good wishes sent by President Obama but also by the breathless news coverage and the general good will toward the actually not-so-young young couple, who have both now reached 30.


First, and least complicated, is the fact that Kate seems a likeable and sensible young woman who married one of the world's most eligible bachelors without letting the power, prestige and A-plus jewelry go to her head.


Then there are the long ties between the two countries, so alike and so maddeningly different.


When Americans proudly declared their independence, they swore off sovereign kings and queens forever, yet several centuries later they find themselves drawn to the royals' pomp and pageantry, embracing the more colorful aspects of a system whose substance they had eagerly overthrown.


Finally, hardest to quantify, is the fading, almost ghostly, image of Princess Diana, who died so young. Americans want Diana's sons to flourish, and Kate seems to have made William very, very happy.


"I remember when Diana died, it was such a shock," said Gitlin, 52. "No one can ever take her place, but it's nice to have another person, someone this generation can look up to, and someone who William can love."


There's no doubt that many Britons are thrilled as well, and the country's embattled tabloid press certainly views a royal pregnancy (at Christmastime no less!) as a surefire circulation booster and a welcome diversion from a series of press scandals.


But some on Monday expressed a rather blasé attitude to the prospect of a new generation of Windsors seemingly bound for the throne. In the chill of early evening in north London's Camden market, young couples strolling among the stalls received the news of Kate's pregnancy with a shrug.


"I'm happy for them, but I don't really care," said Enya Lonergan, 19, who was visiting from Canterbury, south of London, with her friend Will Nichols, 20.


They could muster little enthusiasm for the news, noting that they had little in common with the royals, particularly in these bleak economic times.


"I don't think about them," Nichols said, adding that — naturally — he'd send them a gift. Or not.


Others said they were not interested and questioned the need for a royal family in the 21st century.


"I don't think it's a good thing," said Stephen Jowitt, 63, as he ambled down Camden High Street. "It reinforces a class system."


The news did provide a boost to one of Britain's national pastimes — finding new ways to wager money. Bookmakers are now taking bets on the gender of Kate's child, what the infant will be named and the color of his/her hair.


Joe Crilly, a spokesman for the William Hill bookmaker, said a high level of betting interest is expected, with favored names including Diana, Philip, Elizabeth and Sarah.


In America, ABC News even offered a poll, asking people to rate likely baby names.


Baby thoughts have been found in some less-than-fully-credible supermarket tabloids for months. They've been trumpeting "stories" about Kate's pregnancies for months, without any apparent basis in fact.


But that didn't keep the public from gobbling them up — the British royals, with their haughty glamour and slightly tragic air, have long captivated Americans.


"I'm always looking for any news of William and Kate," said 19-year-old Stacy McFacken, a clerk at a grocery store in Mentor, Ohio, in August when a number of tabloids offered screaming headlines about Kate's purported pregnancy.


"There's nothing like this in the States," she said. "It's just like all the fairy tales we read about as kids. We all want to be Kate."


Word of Kate's condition, including her hospitalization for complications, was top news on websites throughout the world. Her condition requires specialist treatment but if diagnosed early, it is unlikely to have long-term consequences for the mother or baby, and does not raise the risk of a miscarriage.


But while the parents might be anxious, world leaders stepped in to wish her well. The news was featured prominently on front pages in Argentina, India, France, South Africa and other countries. It sent Twitter into a tizzy, with the hashtag "royalbaby" trending worldwide and used more than 28,000 times in the first few hours following the official announcement. U.S. media websites such as People, Vanity Fair and the Daily Beast provided extensive coverage, with the Huffington Post launching a live blog to track developments.


"The whole wide world is excited," said Shao Hua Huang, a surgical nurse who practices in New York and Connecticut. "We're really happy for her. It's because of England and all the tradition. We Americans followed in their footsteps."


___


Associated Press writers Paisley Dodds, Danica Kirka and Cassandra Vinograd in London contributed to this report.


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